Sildenafil Citrate Oral Jelly
Journal of Drug Delivery Science and Technology 2025, 111 , 107193. The Pharmaceutical and Pharmacological Potential Applications of Bilosomes as Nanocarriers for Drug Delivery. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.
Cited By
M. Fabrication of novel ultradeformable bilosomes for enhanced ocular delivery of terconazole: In vitro characterization, ex vivo permeation and in vivo safety assessment. 2016, 513, 688– 696, DOI: 10.1016/j.ijpharm.2016.10.006Google ScholarThere is no corresponding record for this reference. 38Mahmoud, T. M.; Nafady, M.
How is sildenafil supplied (dosage forms)?
M.; Farouk, H. O.; Mahmoud, D. M.; Ahmed, Y. M.; Zaki, R. M.; Hamad, D.
2.6. Stability Study
S. Novel Bile Salt Stabilized Vesicles-Mediated Effective Topical Delivery of Diclofenac Sodium: A New Therapeutic Approach for Pain and Inflammation. In Pharmaceuticals 2022, 15, 1106, DOI: 10.3390/ph15091106Google ScholarThere is no corresponding record for this reference. 39Zafar, A.; Alruwaili, N. K.; Imam, S. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.
| Year | Estimated Market Size (USD) | Growth Rate | Key Factors Influencing Growth |
|---|---|---|---|
| 2023 | 150 million | 8% | Rising prevalence of erectile dysfunction |
| 2024 | 162 million | 8% | Increased acceptance of topical applications |
| 2025 | 175 million | 8% | Advances in transdermal drug delivery technology |
| 2026 | 190 million | 8.5% | Expansion into emerging markets |
References This article references 47 other publications.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Kamagra Soft Tabs | 100mg | 180 + 8 Pills | 425.45€ 405.19€ | |
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Kamagra | 100mg | 84 + 6 Pills | 264.44€ 251.85€ | |
| Viagra Generic | 150mg | 120 + 8 Pills | 177.58€ 169.12€ | |
| Kamagra Soft Tabs | 100mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Viagra Generic | 200mg | 90 + 6 Pills | 170.79€ 162.66€ | |
| Kamagra | 100mg | 20 Pills | 86.09€ 81.99€ | |
| Kamagra Oral Jelly | 100mg | 21 Sachets | 95.92€ 91.35€ | |
| Kamagra Oral Jelly | 100mg | 30 + 5 Sachets | 136.20€ 129.71€ | |
| Kamagra | 100mg | 60 + 4 Pills | 201.34€ 191.75€ |
Journal of Drug Delivery Science and Technology 2020, 55, 101444 DOI: 10.1016/j.jddst.2019.101444There is no corresponding record for this reference.
Precautions of Vega Oral Jelly
Cardiol 2018, 13, 35– 37, DOI: 10.15420/ecr.2017:22:2Google ScholarThere is no corresponding record for this reference. This article is cited by 4 publications. Optimized PEGylated Bilosomes for Oral Delivery of Hesperetin: Formulation and In Vitro Evaluation in Breast Cancer. Compatibility Studies of Sildenafil-HPBCD Inclusion Complex with Pharmaceutical Excipients. Fabrication of PEGylated elastic bilosomes as a potentially effective transdermal delivery of celecoxib for management of osteoarthritis: In vitro characterization, statistical optimization, Ex vivo and In vivo assessments. Aging 2006, 1, 403– 414, DOI: 10.2147/ciia.2006.1.4.403There is no corresponding record for this reference. J. Ther 2019, 26, e520– e526, DOI: 10.1097/MJT.0000000000000766There is no corresponding record for this reference. 2014, 4, 214– 215, DOI: 10.3978/j.issn.2223-4292.2014.06.01There is no corresponding record for this reference.
- Sildenafil gel is sometimes preferred by patients taking multiple oral medications.
- Faster onset possible due to bypassing the digestive tract.
- Avoid concurrent use with medications metabolized by CYP3A4 without advice.
- Storage away from heat and light ensures longer shelf life.
- Gel application site should be clean and dry for best results.
- There is potential for off-label use, but medical guidance is essential.
- Regular assessment avoids misuse or dependence issues.
2015, 61, 181– 192, DOI: 10.4103/0022-3859.159421There is no corresponding record for this reference. BMC Cardiovasc Disord 2017, 17, 177, DOI: 10.1186/s12872-017-0569-3There is no corresponding record for this reference. Children 2023, 10, 270, DOI: 10.3390/children10020270There is no corresponding record for this reference. 2002, 53 (Suppl 1), 5S– 12S, DOI: 10.1046/j.0306-5251.2001.00027.xThere is no corresponding record for this reference. Pharmaceutics 2020, 12, 1124, DOI: 10.3390/pharmaceutics12111124There is no corresponding record for this reference.
Comparison with Other ED Treatments
S.; Hadal Alotaibi, N.; Alharbi, K. S.; Afzal, M.; Ali, R.; Alshehri, S.; Alzarea, S. I.; Elmowafy, M. Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment. 2021, 29, 269– 279, DOI: 10.1016/j.jsps.2021.02.003Google ScholarThere is no corresponding record for this reference.
3.8. Skin Permeation Study
40Duangjit, S.; Pamornpathomkul, B.; Opanasopit, P.; Rojanarata, T.; Obata, Y.; Takayama, K.; Ngawhirunpat, T. Role of the charge, carbon chain length, and content of surfactant on the skin penetration of meloxicam-loaded liposomes. J. Nanomedicine 2014, 9, 2005– 2017, DOI: 10.2147/IJN.S60674Google ScholarThere is no corresponding record for this reference. 41Trotta, M.; Peira, E.; Debernardi, F.; Gallarate, M.
Does sildenafil interact with foods or drinks?
Elastic liposomes for skin delivery of dipotassium glycyrrhizinate. (Elsevier Science B.V.)The aim of this study was to evaluate the possibility of using liposomes for skin delivery of dipotassium glycyrrhizinate (KG), an anti-inflammatory agent employed in treating acute and chronic dermatitis, sildenafil online ireland and of formulating such liposomes in an oil-in-water emulsion (O/W). KG had emulsifying properties and the possibility of producing elastic liposomes was verified. soya lecithin (PC) or hydrogenated soya lecithin (HPC) mixed with KG in wt./wt. method and then passed through a high pressure homogenizer. Colloids Surf., B 2021, 205, 111868 DOI: 10.1016/j.colsurfb.2021.111868There is no corresponding record for this reference.
- Sildenafil gel allows more discreet and flexible dosing schedules.
- It offers an alternative for men experiencing side effects from oral sildenafil.
- Proper hygiene before application reduces infection risk.
- The gel base typically evaporates or absorbs fully without leaving residue.
- The product may be marketed as a cosmetic or pharmaceutical depending on region.
- Some gels have flavor or scent additives to improve user experience.
- Patients should report any adverse skin reactions promptly.
Ther Deliv 2010, 1, 109– 131, DOI: 10.4155/tde.10.1611Challenges and opportunities in dermal/transdermal deliveryPaudel, Kalpana S.; Milewski, Mikolaj; Swadley, Courtney L.; Brogden, Nicole K.; Ghosh, Priyanka; Stinchcomb, Audra L.Therapeutic Delivery (2010), 1 (1), 109-131CODEN: TDHEA7; ISSN:2041-5990. Skin Research and Technology 2008, 14, 249– 260, DOI: 10.1111/j.1600-0846.2008.00316.xThere is no corresponding record for this reference. 2013, 30, 1099– 1109, DOI: 10.1007/s11095-012-0946-7There is no corresponding record for this reference. 2012, 80, 1– 28, DOI: 10.3797/scipharm.1108-20There is no corresponding record for this reference. 2004, 56, 659– 674, DOI: 10.1016/j.addr.2003.10.02715Skin electroporation for transdermal and topical deliveryDenet, Anne-Rose; Vanbever, Rita; Preat, VeroniqueAdvanced Drug Delivery Reviews (2004), 56 (5), 659-674CODEN: ADDREP; ISSN:0169-409X.
Storage Information
P. Transferosomes: A surrogated carrier for transdermal drug delivery system. 2011, 2, 204– 213Google ScholarThere is no corresponding record for this reference. 44Lin, H.; Gebhardt, M.; Bian, S.; Kwon, K. A.; Shim, C.
What should I do if I miss a dose of sildenafil?
K.; Chung, S. J.; Kim, D. D. Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer. 2007, 330, 23– 31, DOI: 10.1016/j.ijpharm.2006.08.043Google ScholarThere is no corresponding record for this reference.
Other Medical Problems
45Moghimipour, E.; Ameri, A.; Handali, S. Absorption-Enhancing Effects of Bile Salts. properties of bile salts are lipid transport by solubilization and transport of some drugs through hydrophobic barriers. Bile salts have been extensively studied to enhance transepithelial permeability for different marker mols. The mechanism of absorption enhancement by bile salts appears to be complex. 2008, 60, 1218– 1223, DOI: 10.1016/j.addr.2008.03.006There is no corresponding record for this reference. 2003, 23, 763– 793, DOI: 10.1002/med.10048There is no corresponding record for this reference. 2001, 14, 101– 114, DOI: 10.1016/S0928-0987(01)00167-118Novel mechanisms and devices to enable successful transdermal drug deliveryBarry, B. W.European Journal of Pharmaceutical Sciences (2001), 14 (2), 101-114CODEN: EPSCED; ISSN:0928-0987. 2003, 29, 1013– 1026, DOI: 10.1081/DDC-120025458There is no corresponding record for this reference. 2009, 1, 15– 26, DOI: 10.5138/ijdd.2009.0975.0215.01002There is no corresponding record for this reference. Journal of Young Pharmacists 2016, 8, 335– 340, DOI: 10.5530/jyp.2016.4.8There is no corresponding record for this reference.
Content area
The aim of the present article was to review bile salt structure and their application as absorption enhancers and the probable mechanism for increasing permeation based on previous studies. 46Chen, C. N.; Watson, G.; Zhao, L. Cyclic guanosine monophosphate signalling pathway in pulmonary arterial hypertension. Vascul Pharmacol 2013, 58, 211– 218, DOI: 10.1016/j.vph.2012.09.001Google ScholarThere is no corresponding record for this reference. 2021, 11, 442– 451, DOI: 10.1039/D0RA09561CThere is no corresponding record for this reference. Artificial Cells, Nanomedicine, and Biotechnology 2015, 43, 282– 290, DOI: 10.3109/21691401.2014.883401There is no corresponding record for this reference.
| Ingredient | Concentration | Purity (%) | Solvent Used | pH Level | Preservatives |
|---|---|---|---|---|---|
| Sildenafil Citrate | 10 mg/g | 99.5 | Propylene Glycol | 5.5 | Methylparaben |
| Glycerin | -- | -- | -- | -- | -- |
| Carbomer | 1.5% | -- | -- | -- | -- |
| Ethanol | 2% | -- | -- | -- | -- |
| Purified Water | q.s. to 100g | -- | -- | -- | -- |
2010, 99, 2357– 2366, DOI: 10.1002/jps.22004There is no corresponding record for this reference. 2006, 322, 60– 66, DOI: 10.1016/j.ijpharm.2006.05.02725Deformable liposomes and ethosomes: Mechanism of enhanced skin deliveryElsayed, Mustafa M.
| Step | Procedure | Tips | Precautions |
|---|---|---|---|
| 1 | Clean and dry the application area | Use alcohol wipes for cleanliness | Avoid open wounds |
| 2 | Apply a small amount (about 0.5 g) evenly | Use applicator if provided | Do not overdose |
| 3 | Allow absorption for 10-15 minutes | Do not massage vigorously | Avoid bathing immediately after |
| 4 | Wash hands thoroughly afterward | Prevent inadvertent transfer to other areas | Keep out of reach of children |
A.; Abdallah, Ossama Y.; Naggar, Viviane F.; Khalafallah, Nawal M.International Journal of Pharmaceutics (2006), 322 (1-2), 60-66CODEN: IJPHDE; ISSN:0378-5173. Drug Deliv 2018, 15, 122– 133, DOI: 10.2174/1567201814666170224141548There is no corresponding record for this reference. Gels 2022, 8, 235, DOI: 10.3390/gels8040235There is no corresponding record for this reference. J. Nanomedicine 2020, 15, 9783– 9798, DOI: 10.2147/IJN.S278688There is no corresponding record for this reference.
Uses of Vega Oral Jelly
Liposome size and entrapment efficiency were detd. and the interaction between KG and HPC was investigated using differential scanning calorimetry. Transepidermal permeation through intact pig skin and skin deposition of KG from liposomes and O/W emulsion contg. liposomes were assessed and compared with values for aq. Liposome sizes ranged from 90 to 120 nm.
3.4. Stability Studies
Entrapment efficiency depended on the lipid:KG ratio; the max. efficiency was obtained at 4:1 wt./wt. KG interacted with liposomes disrupting and fluidizing the lipid bilayer, forming elastic liposomes able to penetrate through membrane pores of diam. The liposome structure was maintained when dispersed in an O/W emulsion. The skin fluxes were less than the HPLC detection limit for all systems, while skin deposition increased 4.5-fold compared with aq.
Who should not take sildenafil?
Novel Enhanced Therapeutic Efficacy of Dapoxetine HCl by Nano-Vesicle Transdermal Gel for Treatment of Carrageenan-Induced Rat Paw Edema. AAPS PharmSciTech 2020, 21, 113, DOI: 10.1208/s12249-020-01656-6Google ScholarThere is no corresponding record for this reference. 43Walve, J. R.; Bakliwal, S.; Rane, B. R.; Pawar, S. Drug Discov Today 2016, 21, 888– 899, DOI: 10.1016/j.drudis.2016.03.013There is no corresponding record for this reference.