Clinical Evidence for Tadalafil 5 mg Daily Use

This is the highest dosage that a doctor may prescribe. If you’re prescribed Cialis for daily use, the typical starting dosage is 2.5 mg taken once per day. If this dosage is not effective for you, your doctor may increase your dosage to 5 mg per day. You do not have to take Cialis at any specific time before sexual activity when it’s prescribed in this way. You can take your dose at any time of day. But you should try to take it at the same time every day. This helps ensure there’s enough medication in your body for Cialis to be effective.

Key Takeaway 5

As it’s the unbranded version, the tadalafil 10mg price will be slightly cheaper. The 10mg dose works for around 71% of men and has a lower risk of side effects than the 20mg dose. If you’re starting treatment with Cialis daily, you’ll normally be prescribed Cialis 2.5mg. This is the lowest daily dose available. The unbranded, generic version is Tadalafil 2.5mg which once again is usually at a lower price point.

Take as directed

But your physician can increase or decrease your dose based on your response to the treatment. This is to keep the risk of side effects low — your doctor will aim for the lowest dose possible to get the job done. (Which is 2.5mg for ‘daily’ use, and 10mg for ‘on-demand’ use. If your ‘on-demand’ dose doesn’t work well enough, your clinician may increase it to 20mg. And similarly, if your daily dose of 2.5mg isn’t working as well as you’d like, it can then be increased to 5mg.

Who should not use tadalafil?

If you experience side effects on Cialis, let your doctor or pharmacist know. They’ll suggest either lowering your dose or recommend an alternative ED treatment. To minimize the risk of side effects avoid grapefruit, drinking too much alcohol, and do not take more than one dose of Cialis per day. If you aren’t seeing the results you want on Cialis Daily 2.5mg, and don’t experience side effects, your prescriber may recommend upping your dose to Cialis 5mg daily. It should be equally as effective at treating ED as Cialis. The typical dosage of Cialis for occasional use in treating ED is 10 mg taken before sexual activity. If you have side effects with the 10-mg dose, your doctor may reduce your dose to 5 mg.

Product	Dosage	Quantity + Bonus	Price
Cialis Professional	40mg	90 + 2 Pills	348.59€ 331.99€	Buy
Cialis Original	20mg	76 + 4 Pills	319.19€ 303.99€	Buy
Cialis Generic	5mg	10 Pills	29.39€ 27.99€	Buy
Cialis Generic	5mg	270 + 10 Pills	205.81€ 196.01€	Buy
Cialis Generic	40mg	360 + 10 Pills	477.87€ 455.11€	Buy
Cialis Generic	40mg	180 + 10 Pills	277.29€ 264.09€	Buy
Cialis Generic	2.5mg	120 + 6 Pills	128.93€ 122.79€	Buy
Cialis Super Active	20mg	120 + 16 Pills	382.15€ 363.95€	Buy
Cialis Super Active	20mg	30 + 6 Pills	128.09€ 121.99€	Buy
Cialis Original	20mg	14 + 2 Pills	95.75€ 91.19€	Buy
Cialis Black	80mg	90 + 6 Pills	207.88€ 197.98€	Buy

If the 10-mg dose doesn’t work for you, they may increase your dose to the maximum recommended dosage of 20 mg per day.

Why is this medication prescribed?

There is no Cialis 40mg or Tadalafil 40mg available in the US. A tadalafil dosage of 40mg is used to treat pulmonary arterial hypertension, but this is under careful medical supervision. Doses higher than 20mg have a higher risk of side effects and can dangerously affect blood pressure. One such side effect, priapism, is an erection that lasts more than 4 hours and requires immediate medical attention. At your consultation, make sure you give your doctor your full medical history.

Dosage adjustments

This will help them make the best initial decision about your erectile dysfunction treatment. Once you begin treatment, keep an eye out for any side effects and let your prescriber know if they occur. Whilst it’s important you give your prescribed dose a few tries, it should ultimately offer you the results you want. If this isn’t the case, again, let your clinician know. Getting the best results when you take Cialis is the end goal.

Muscular Dystrophy (Orphan)

Always follow the instructions in the leaflet or on the pack and any specific guidance given to you by your doctor. If you’re taking Cialis as needed, remember to give it enough time to work. Results aren’t instant, so aim for no less than 30 minutes before sex — longer if possible. Avoiding mixing Cialis with nitrates, such as isosorbide mononitrate or GTN spray. These cause a drop in blood pressure, which can be dangerous and never take double doses or split doses. When taken for occasional use to treat ED, the effects of Cialis have been reported to last up to 36 hours. Regardless of the prescribed dose, you should not take more than one Cialis tablet per day. For treating BPH, the recommended Cialis dosage is 5 mg taken once per day.

• Realistic expectations: may not result in an erection every time.
• Sexual stimulation is still required for an erection to occur.
• Can be part of a healthy lifestyle including diet and exercise.
• Smoking can worsen ED and reduce treatment effectiveness.
• Managing underlying conditions like diabetes improves outcomes.
• Psychological counseling may be needed alongside medication.
• There is no tolerance build-up; efficacy is maintained long-term.
• Abrupt discontinuation does not cause withdrawal symptoms.
• Not a performance-enhancing drug for athletes; banned in some sports.
• Using more than one dose in 24 hours increases side effect risk.

For use as a single medication to treat both ED and BPH, the recommended Cialis dosage is 5 mg taken once per day. You don’t have to take Cialis at any specific time before sexual activity when it’s prescribed in this way. Doctors recommend using Cialis as a long-term treatment, even if you take it only on occasion to treat ED.

• Adherence to the daily schedule is important for consistent results.
• Efficacy for ED in clinical trials measured by validated questionnaires.
• Improvement in International Index of Erectile Function score is typical.
• For BPH, improvement in International Prostate Symptom Score is seen.
• The medication relaxes the detrusor muscle in the bladder wall.
• Also causes relaxation of smooth muscle in the prostate and urethra.
• Does not significantly affect PSA levels for prostate cancer screening.
• May be used by men who have undergone prostate surgery.
• Consult a urologist for persistent ED or urinary symptoms.
• Keep all medications out of reach of children and pets.

If you and your doctor determine that Cialis is safe and effective for you, you’ll likely take it long term. The following are some answers to frequently asked questions about Cialis dosages. The maximum recommended dosage of Cialis is 20 mg once per day.

Using Cialis With Food

Cialis (tadalafil) is a brand-name drug used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). The typical dosage of Cialis depends on the condition it’s being used to treat. And for ED, the dosage depends on whether it’s taken daily daily cialis buy or as needed. The maximum recommended dosage for ED or BPH is 20 mg per day. Your doctor may adjust your Cialis dosage based on factors such as other medications you take, whether you experience bothersome side effects, and whether you have kidney or liver problems.

Erectile Dysfunction

Cialis belongs to a drug class called phosphodiesterase-5 (PDE5) inhibitors. It is available in a generic version. This article describes the dosages of Cialis, as well as its available strengths and how to take it. The following information describes dosages that are commonly used or recommended for Cialis. Be sure to take the dosage your doctor prescribes for you.

Data extraction

They’ll determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those mentioned here. Cialis comes as an oral tablet in four strengths: 2.5 milligrams (mg), 5 mg, 10 mg, and 20 mg. Cialis is approved to treat the following conditions: Note: Some people may be prescribed Cialis to treat both ED and BPH. Whichever condition Cialis is used to treat, the recommended maximum dose per day is 20 mg. Taking a higher dose of Cialis than recommended could increase your risk for side effects. These can include serious side effects such as drops in blood pressure or priapism (a painful erection that won’t go away). It’s important not to take more Cialis than the dose your doctor recommends. You should take Cialis exactly as it’s prescribed for you. If you have other questions about Cialis doses, talk with your doctor or pharmacist. Cialis dosages for someone who is age 70 years (and older adults in general) are the same as those for other adults. For recommended doses, see the “Cialis dosage” section. Older adults may be more sensitive to the effects of Cialis. Because of this, your doctor may prescribe a lower dose than usual when you start taking Cialis.

The drug Cialis is popular because you can take it every day. But should you?

2004.The efficacy and safety of tadalafil: an update. Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: A dose finding study. The Journal of Urology, 180(4), 1228-1234 Coward, Robert M., Carson, Culley C. 2008. A comparison of the efficacy and tolerability of tadalafil 10 mg and 20 mg in Japanese patients with severe erectile dysfunction.

Related treatment guides

The journal of sexual medicine, 4(3), pp.745–752. This page was medically reviewed by Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer on Sep 03, 2025. Next review due on Sep 03, 2028. When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body.

Drug Interactions

We couldn't find what you're looking for. Or, if you're looking for something we don't have yet, you can suggest something. All of our reviews are collected from real patients after their treatment has been delivered. We publish reviews collected through independent platforms including Reviews.io and Trustpilot. Why this page was updated on Sep 19, 2025 Content checked and updated as part of our 3-yearly periodic review, to ensure accuracy and currentness. Then, if needed, they can adjust it over time to reach the amount that’s right for you. If you have additional questions about the use of Cialis in older adults, talk with your doctor or pharmacist. It’s important that you do not use more Cialis than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose. Call your doctor right away if you believe you’ve taken too much Cialis. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool.

Condition	Recommendation	Notes
Nitrate use	Do not use concurrently	Risk of severe hypotension
Severe liver impairment	Consult doctor before use	Adjusted dosing may be necessary
Heart conditions	Caution; consult healthcare provider	Especially for unstable angina
Retinitis pigmentosa	Use with caution	Eye health considerations
Hypotension (<90/50 mmHg)	Avoid use	Blood pressure management

If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room. The Cialis dosage your doctor prescribes will depend on several factors. the type and severity of the condition you’re using Cialis to treat side effects that you may have from taking Cialis how well the medication is working for you, if used to treat erectile dysfunction (ED) Other medical conditions you have can also affect your Cialis dosage. If you have kidney or liver problems, your doctor may adjust your Cialis dosage. If the kidney or liver problems are mild or moderate, you’ll likely need a lower dose of the drug than usual. Keep in mind that if you have severe liver problems, you should not use Cialis. The drug is also not recommended for daily use if you have severe kidney problems. Your doctor can determine the severity of your kidney or liver problems and whether Cialis is a safe medication for you to take. Talk with your doctor or pharmacist if you have questions about Cialis dosage adjustments. You can take them with or without food.

• PDE5 inhibitors like Cialis may have protective cardiac effects studied.
• Theories include improved endothelial function and reduced oxidative stress.
• These potential benefits are not a reason for prescription without ED/BPH.
• Never share your prescription medication with another person.
• A friend's positive experience does not guarantee your safety or results.
• Dosage is highly individualized based on health and response.
• Keeping a symptom diary can help your doctor assess effectiveness.
• Follow-up appointments are crucial to monitor benefits and side effects.
• Treatment can be discontinued at any time under doctor's guidance.
• Newer treatments may emerge; stay informed with your physician.

If you take Cialis for occasional use to treat erectile dysfunction (ED), you should take your dose before sexual activity. If you take Cialis daily for ED, benign prostatic hyperplasia (BPH), or both, you can take your dose at any time of day. But you should try to take your dose at the same time every day. You should not take more than one dose of Cialis per day.

• A treatment option for men with both ED and BPH (common combo).
• Potential for improved quality of life and self-esteem.
• Open communication with your partner about treatment is beneficial.
• Does not cause infertility; may actually aid in conception efforts.
• Sperm parameters are not negatively affected by tadalafil.
• There is no evidence it causes permanent retinal damage.
• Most side effects are mild to moderate and diminish over time.
• Back pain is thought to be due to PDE11 inhibition in muscle.
• Staying well-hydrated may help mitigate muscle-related side effects.
• Driving and operating machinery are usually safe while taking it.

Be sure not to take more of the drug than your doctor prescribes for you.